Dott.ssa Mariafrancesca SCALISE
 

 

Researcher of Biochemistry

SSD: BIO/10

DiBEST
Ponte Pietro Bucci
Cubo 4C – floor 4

PHONE: +39 0984/492938

EMAIL: mariafrancesca.scalise@unical.it

 

   RESEARCH INTERESTS
 MEMBRANE TRANSPORTERS BIOCHEMISTRY:
- Protein purification by chromatographic techniques using FPLC application.
- Transport measurements by radioisotope and fluorescence techniques.
- Over-expression in human cells and transport assays in intact cells.
- Transport assays in artificial membrane system (proteoliposomes).
- Membrane transport mechanisms and structure/function relationships (homology modeling, site
- directed mutagenesis and chemical labeling).
- Evaluation of effects of endogenous and exogenous compounds
- Evaluation of involvement of the studied proteins in human pathologies: cancer, diabetes, inflammatory diseases. 

MEMBRANE TRANSPORTERS UNDER INVESTIGATION:
- Amino acid transporters: hASCT2, hLAT1, hSLC38A9, SlCAT2.
- Sialic acid transporter: SiaT of pathogenic bacteria
- Organic cation transporters: OCTN1, OCTN2, OCTN3 

 

   LABORATORIES

 - Unit of Biochemistry and Molecular Biotechnologies Cubo 4C IV floor; 

 

   PUBBLICATIONS

- https://www.ncbi.nlm.nih.gov/pubmed/?term=scalise+m+and+indiveri+c

- https://www.scopus.com/authid/detail.uri?authorId=25824484100  

 

   TEACHING COURSES

 27005600 - BIOCHIMICA E BIOLOGIA MOLECOLARE APPLICATE - BIOCHIMICA E BIOLOGIA MOLECOLARE APPLICATE AFFINE - Doc. SCALISE Mariafrancesca (CdS 0734 Patologico-molecolare - Biologia Forense)