DFSSN

Dipartimento di
Farmacia e Scienze della Salute e della Nutrizione
Dipartimento di Eccellenza L. 232/2016

  • Dipartimento di Farmacia e Scienze della Salute e della Nutrizione

 

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Dr Adele CHIMENTO

 

education

2008: Ph.D in “Molecular Biopathology”, Faculty of Mathematical, Physical and Natural Sciences, University of Calabria, Rende, Italy.

2008: Residency in Clinical Pathology, Faculty of Pharmacy, University of Calabria, Rende, Italy (70/70 cum laude).

2000: Qualification to Pharmacist profession, University of Calabria, Rende, Italy.

1999: Degree in Pharmacy, Faculty of Pharmacy, University of Calabria, Rende, Italy (110/110 cum laude).

professional experience

2020 to present: Assistant Professor in Applied Biology (BIO/13), Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.

2009-2020: Laboratory Technician at the Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.

2008Postdoctoral Fellowship at the Laboratory of Estrogens and Reproduction, Prof. Serge Carreau director of CNRS (Scientific Research National Center), Department of Biochemistry, University of Caen Basse-Normandie, France.

Qualification:

2017-2026: National Scientific Qualification as Associate Professor in Applied Biology (05/F1).

2017-2026: National Scientific Qualification as Associate Professor in General Biochemistry (05/E1).

2014-2023: National Scientific Qualification as Associate Professor in Applied Biology (05/F1).

Research experiences:

2004-2007: Ph.D student in “Molecular Biopathology”, Faculty of Mathematical, Physical and Natural Sciences, University of Calabria, Rende, Italy.

2000-2008: Resident in Clinical Pathology, Faculty of Pharmacy, University of Calabria, Rende, Italy.

Participation to National Grants

2018 to present: Component research unit, (AIRC, IG 2017, Id. 20122) “Estrogen Related Receptor α (ERRα) a key metabolic factor as target to prevent Adrenocortical Cancer progression”.

2016-2018: Component research unit, (AIRC, IG 2014, Id. 15230) “The Endogenous Selective Estrogen Receptor Modulator 27-Hydroxycholesterol: a new Modulator of Adrenocortical Cancer”.

2014-2017: Component research unit, (AIRC, IG 2013, Id. 14433) “Selective estrogen receptor modulators (SERMs): a new tool for targeted therapy in adrenocortical cancer”.

2010-2013: Component research unit, (AIRC, IG 2010, Id.10344) “Integration of signaling pathways in adrenocortical carcinomas: New insights for new therapeutic approaches”.

 

Patent

2019: “6,6a-diidro furo[3,2-b]furan-2-(5h)one derivatives, their preparations and use for treating tumors” (European Patent,  n°: EP3428169 A1 ? 2019-01-16).

research fields

Main research fields:

· Molecular mechanisms involved in adrenocortical cancer (ACC) development: role of ERα (Estrogen Receptor Alpha), IGF1R (Insulin-Like Growth Factor 1 Receptor), PELP1 (Scaffold Protein Proline, Glutamic Acid-, and Leucine-Rich Protein 1), GPER (G Protein-Coupled Estrogen Receptor 1), EGR-1 (Early Growth Response Gene-1) and ERRα (Estrogen-Related Receptor Alpha).

· Role of Cholesterol and 27-Hydroxycolesterol in adrenocortical cancer progression.

· Role of Estrogen Receptors and GPER in spermatogenesis and testicular tumors.

· Study of potential anticancer activities of natural or newly synthesized compounds in tumor cell models.

Publications

Scopus: https://www.scopus.com/authid/detail.uri?authorId=6506513887

WoS: https://app.webofknowledge.com/author/record/1173616

 

teaching activity

2018 -2019: "Applied Biology", Inter-University Degree Course in Healthcare Assistance, DFSSN, Magna Grecia University of Catanzaro-University of Calabria.

2017 - 2018: "Cell Biology", Degree Course in Pharmacy, Department of Pharmacy, Health and Nutritional Sciences, University of Calabria.

2017: "Cell Biology", Degree Course in Pharmacy, Department of Pharmacy, Health and Nutritional Sciences, University of Calabria.

2016: "Applied Biology- Nutraceuticals and signal transduction mechanisms at cellular level", II level Master in "Nutrition and Nutraceutical Integration", Department of Pharmacy, Health and Nutritional Sciences, University of Calabria.

2015: "Applied Biology- Nutraceuticals and signal transduction mechanisms at cellular level", II level Master in "Nutrition and Nutraceutical Integration", Department of Pharmacy, Health and Nutritional Sciences, University of Calabria.

2013: "Nutraceuticals and Signal Transduction Mechanisms at Cellular Level", II Level Master in "Nutraceutical Integration: from Wellness to the cure ", Department of Pharmacy, Health and Nutritional Sciences, University of Calabria.

 

teaching Unit

 

“Methods for the study of the effects of nutrients on cellular processes”/ “Metodi per lo studio degli effetti dei nutrienti sui processi cellulari”, Course Link: https://www.unical.it/portale/portaltemplates/view/view_scheda_insegnamento.cfm?79859&LANG=ITA&79859&LANG=ITA