DFSSN

Dipartimento di
Farmacia e Scienze della Salute e della Nutrizione
Dipartimento di Eccellenza L. 232/2016

  • Dipartimento di Farmacia e Scienze della Salute e della Nutrizione

 

 

 

 

 

 

 

Prof Diana AMANTEA

 

education

2003: PhD in Pharmacology, Medical School, University of Birmingham (UK)

1999-2000: Post-graduate specialization (MIUR fellowship), Pharmacology Department, Neuroscience Division, University of Birmingham (UK)

1998: PharmD (Pharmaceutical Chemistry and Technology Degree) cum laude, Faculty of Pharmacy, University of Calabria (IT)

professional experience

2014-present: Associate Professor of Pharmacology (SSD BIO14), Department of Pharmacy, Health and Nutritional Sciences, University of Calabria

2011-present: Head of the Stroke Research Unit, Section of Preclinical and Translational Pharmacology, University of Calabria (operating in the framework of the Stroke Centre and Emergency Neurology Trust, IRCCS Mondino Foundation, Pavia)

2009: Visting researcher (MIUR fellowship) - Neurovascular Research Unit (group leaders: M.A. Moro and I. Lizasoain), Departamento de Farmacología, Facultad de Medicina, Universidad Complutense, Madrid (Spain)

2008: Visting researcher (regional voucher): Département de Biologie Cellulaire et de Morphologie (group leader: Dr P. Bezzi), Université de Lausanne (CH)

2005-2014: Research Fellow (SSD BIO14: Pharmacology), School of Pharmacy, University of Calabria

2005-2006: Visiting researcher – Experimental Neurology Laboratory (group leader: N. Mercuri), IRCCS Santa Lucia Foundation (Rome)

2003: Honorary Research Fellow, Department of Pharmacology, Birmingham University (UK)

 

National scientific qualification (L. 240/2010):

12/04/2017: Full Professor of Pharmacology, Clinical Pharmacology and Pharmacognosy (05/G1)

Editorial activity:

- Editorial Board Member of Frontiers in Neurology-Stroke (from 2019), Frontiers in Molecular Neuroscience (from 2019), Current Opinion in Pharmacology (from 2015), ISRN Neurology (from 2013), ISRN Stroke (from 2012)

- Guest Editor for the 2016 Neuroscience section of Current Opinion in Pharmacology (Elsevier)

- Editor of “Rational Basis for Clinical Translation in Stroke Therapy” (ISBN: 978-1-4665-94975), CRC Press, Taylor and Francis Group, Boca Raton, FL, USA, (2014)

- Founder and Editor of the series "Frontiers in Neurotherapeutics" (CRC Press, Taylor & Francis group, USA) from 2012

 

managerial/department role

2019-present: Member of the Board of the Department of Pharmacy, Health and Nutritional Sciences of the University of Calabria.

2008-2018: Delegate for the coordination of the Orientation activities of the Department of Pharmacy, Health and Nutritional Sciences of the University of Calabria.

 

research fields

Main research topic:

Characterization of the interactions between the immune system and the brain subjected to ischemic injury for the identification of novel pharmacological targets for stroke therapy.

 

Research projects:

Exploitation of circulating miRNAs for diagnosis and neuroprotection in translational stroke studies”, PRIN2017 (role: researcher)

“Calcium release-activated calcium modulator 1 (ORAI-1) and Stromal interaction molecule 1 (STIM1) in brain ischemic preconditioning as new targets to reprogram the innate immune system and induce tolerance in neurons”, PRIN2015 (role: RU coordinator)

“Role of the transcription factor STAT3 in the inflammatory response at the level of the neurovascular unit in an experimental model of “stroke”. Implications for the development of neuroprotective drugs”, PRIN2008 (role: researcher)

“Regulation of the expression of matrix metalloproteinases in cerebral ischemia”, MIUR, Integrated actions Italy-Spain 2008 (role: researcher)

“Role of matrix proteases in the early and late expression of detrimental mediators in rat brain ischemia”, PRIN2006 (role: researcher)

“Study of the mechanisms of neuroprotection exerted by estrogens in an experimental model of ischemia-reperfusion in the brain of rat”, PRIN2004 (role: researcher)

“Study of the mechanisms of neuronal death in experimental models of excitotoxicity in vivo”, PRIN2002 (role: researcher)

 

publications

ORCID: https://orcid.org/0000-0002-7513-3495

Scopus: https://www.scopus.com/authid/detail.uri?authorId=6506830470

 

teaching activity

Undergraduate courses:

“Elements of Pharmacokinetics, Pharmacodynamics and Pharmacotherapy” and “Toxicokinetics and Toxicodynamics” (Degree course: Scientific Information on Drugs and Health Products, University of Calabria) – from AY 2015/16

“General Pharmacology with elements of Pharmacognosy” (Degree Course: Pharmaceutical Chemistry and Technology, University of Calabria) - from AY 2013/14

“Cellular Toxicology” (Degree Course: Pharmacy, University of Calabria) - from AY 2006/07 to 2015/16

“General, Cellular and Molecular Pharmacology” (Degree Course: Pharmaceutical Chemistry and Technology, University of Calabria) - from AY 2003/04 to 2012/13

Tutor for the course “Pharmacology for medical students” (Medical School, University of Birmingham, UK) - AY 2002/2003

 

PhD Academic Board Member:

“Translational Medicine” (University of Calabria) – from 2013

“Cellular Biochemistry and Drug Activity in Oncology” (University of Calabria) – from 2008 to 2012

“Pharmacology and Biochemistry of Cell Death” (University of Calabria) – from 2005 to 2007

 

Member of PhD dissertation committee:

“Biochemistry, Molecular Biology and Biomedicine”, Medical School, Complutense University of Madrid (Spain) – 07/2017

“Biomedical Sciences and Pharmacy”, Department of Drug Technology and Social Pharmacy of the Medical Academy of Lithuanian University of Health Sciences (Lituania)

 

Master courses:

“Pharmacology” module (teaching unit: Pharmacology, anaesthesia and intensive care), 2nd level Master Degree in “Urgent care and emergency medicine”, University of Calabria (02/2019)

 

teaching Units

 

Farmacologia Generale con Elementi di Farmacognosia - General Pharmacology with elements of Pharmacognosy (https://www.unical.it/portale/portaltemplates/view/view_scheda_insegnamento.cfm?51332)

 

Elementi di Farmacocinetica, Farmacodinamica e Farmacoterapia - Elements of Pharmacokinetics, Pharmacodynamics and Pharmacotherapy (https://www.unical.it/portale/portaltemplates/view/view_scheda_insegnamento.cfm?60996&LANG=ITA&60996&LANG=ITA)

 

Tossicocinetica e Tossicodinamica - Toxicokinetics and Toxicodynamics (https://www.unical.it/portale/portaltemplates/view/view_scheda_insegnamento.cfm?60997&LANG=ITA&60997&LANG=ITA)